How behaviour changes with correlates of age in unicellular organisms remains an open question.
The main reason for this might be that single-cell organisms were mistakenly believed to be short-lived and immune to ageing.
It has now been demonstrated that some unicellular organisms such as bacteria, paramecia and yeast, undergo intrinsic changes over time that affect their behavior and physiology.
In this study, Audrey Dussutour, Angèle Rolland, Emilie Pasquier, Paul Malvezin, Cassandra Craig and Mathilde Dumas (CRCA-CBI) studied how the behavior of the slime mold Physarum Polycephalum, a unicellular organism, varies over the lifetime of individuals, and they showed that aging in the blob might be partially reversible.
Behavioural changes in slime moulds over time
A. Rolland, E. Pasquier, P. Malvezin, C. Craig, M. Dumas et A. Dussutour
Philosophical Transactions of the Royal Society B le 20 février 2023. DOI:https://doi.org/10.1098/rstb.2022.0063